pediatric meningoencephalitis; a research on patients hospitalized in zahedan, southeastern iran

نویسندگان

ali khajeh children and adolescents health research center, aliebn-e-abitaleb hospital, zahedan university of medical sciences, zahedan, ir iran

batool sharifi-mood infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran; infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran. tel: +98-54133228101-2, fax: +98-5433236722

gholam reza soleimani children and adolescents health research center, aliebn-e-abitaleb hospital, zahedan university of medical sciences, zahedan, ir iran

چکیده

background meningitis is a life-threatening disease and can lead to significant sequelae. pediatric bacterial meningitis leaves some survivors with more significant sequelae if not treated, promptly. the advent of vaccine has changed the incidence of pediatric bacterial meningitis but these vaccines have not been used in routine childhood immunization schedule. objectives the current study aimed to investigate the epidemiology, clinical features, etiologic agents and clinical outcome of meningencephalitis among the pediatric group in zahedan, iran. patients and methods the current cross-sectional and descriptive study investigated the medical records of the patients with meningitis from may 2010 to may 2014. then, the patients were evaluated according to sex, age, clinical feature, risk factor, etiologic agents, acute or chronic form, and clinical outcome. results among 55 patients with meningitis (42% girls and 58% boys; mean age of 8.5 months, age range of 45 days to nine years), 55 cases (98%) had acute meningoencephalitis and only one case (2%) had chronic tuberculous (tb) meningitis. out of the 54 cases with acute disease, only six cases showed a positive test for etiologic agent. forty-eight patients had negative csf culture. the most common clinical symptom was fever (95%) and the least was seizure (16%). mortality rate was 7.2% (four cases). there were no significant risk factors in children with illness, but there was a history of pulmonary tb in grandmother of the case with tb meningitis. conclusions according to the obtained results, and finding a high negative cerebro-spinal fluide (csf) culture in acute meningitis, it is recommended to use systems to detect the bacteria more, particularly in the patients whose parents use antibiotics before referring to a physician. also, more specific viral tests are needed to detect the etiologic agents of viral meningitis.

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عنوان ژورنال:
international journal of infection

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